Nos dernières publications

Plasma transfusion in the intensive care unit

Van Haeren MMT, Raasveld SJ, de Bruin S, Reuland MC, van den Oord C, Schenk J, Aubron C, Bakker J, Cecconi M, Feldheiser A, de Grooth HJ, Meier J, Scheeren TWL, McQuilten Z, Flint A, Hamid T, Piagnerelli M, Mahečić TT, Benes J, Russell L, Aguirre-Bermeo H, Triantafyllopoulou K, Chantziara V, Gurjar M, Myatra SN, Pota V, Elhadi M, Gawda R, Mourisco M, Lance M, Neskovic V, Podbregar M, Llau JV, Quintana-Diaz M, Cronhjort M, Pfortmueller CA, Yapici N, Nielsen ND, Shah A, Vlaar APJ, Müller MCA; InPUT Study Group.

Transfusion. 2025 Jan;65(1):73-87. doi: 10.1111/trf.18071. Epub 2024 Dec 18.

PMID: 39696779 

Association between red blood cell transfusion and adverse clinical outcomes is Independent of cardiac history: a multicenter observational InPUT study analysis.

Kimmoun A, Girerd N, Duarte K, Bruno J, Schenk J, Levy B, Baudry G, Raasveld SJ, de Bruin S, Reuland MC, van den Oord C, Schaap CM, Bakker J, Cecconi M, Feldheiser A, Meier J, McQuilten Z, Müller MCA, Scheeren TWL, Aubron C, Flint AWJ, Hamid T, Piagnerelli M, Mahečić TT, Benes J, Russell L, Aguirre-Bermeo H, Triantafyllopoulou K, Chantziara V, Gurjar M, Myatra SN, Pota V, Elhadi M, Gawda R, Mourisco M, Lance M, Neskovic V, Podbregar M, Llau JV, Quintana-Diaz M, Cronhjort M, Pfortmueller CA, Yapici N, Nielsen N, Shah A, de Grooth HJ, Vlaar APJ, Mebazaa A; InPUT study Group.Crit Care. 2025 Dec 18;29(1):526. doi: 10.1186/s13054-025-05745-5.PMID: 41413913 

Global transfusion practices in septic patients in the intensive care unit: insights from the InPUT-study sub-analysis.

Kurucz VC, Flint AWJ, Poole A, Reuland MC, van den Oord C, Schaap CM, Bakker J, Cecconi M, Feldheiser A, Meier J, McQuilten Z, Müller MCA, de Bruin S, Scheeren TWL, Hamid T, Aubron C, Piagnerelli M, Mahečić TT, Benes J, Russell L, Aguirre-Bermeo H, Triantafyllopoulou K, Chantziara V, Gurjar M, Myatra SN, Pota V, Elhadi M, Gawda R, Mourisco M, Lance M, Neskovic V, Podbregar M, Llau JV, Quintana-Diaz M, Cronhjort M, Pfortmueller CA, Yapici N, Nielsen N, Shah A, de Grooth HJ, Vlaar APJ, Schenk J, Raasveld SJ; InPUT Study Group.Transfusion. 2025 Oct 22. doi: 10.1111/trf.18445. Online ahead of print.PMID: 41122832

Prevalence of thromboembolic events in critically-ill COVID-19 patients infected with Omicron: results from the French prospective, multicenter SEVARVIR cohort study.

Bay P, Audureau E, Fourati S, de Prost N; SEVARVIR investigators.Crit Care. 2025 Jun 10;29(1):234. doi: 10.1186/s13054-025-05473-w.

Clinical Phenotypes of Critically Ill Patients with COVID-19 Infected with Omicron: A Nationwide Prospective Cohort Study.

Audureau E, Bay P, Préau S, Favory R, Guigon A, Heming N, Gault E, Pham T, Chaghouri A, Turpin M, Morand-Joubert L, Jochmans S, Pitsch A, Meireles S, Contou D, Henry A, Roux D, Le Hingrat Q, Kimmoun A, Hartard C, Pène F, L'Honneur AS, Guillon A, Handala L, Tamion F, Moisan A, Daix T, Hantz S, Delamaire F, Thibault V, Darreau C, Thomin J, Pawlotsky JM, Fourati S, de Prost N; SEVARVIR investigators.Infect Dis Ther. 2026 Jan 6. doi: 10.1007/s40121-025-01291-3. Online ahead of print. PMID: 41493514

Inhaled Sedation in Acute Respiratory Distress Syndrome: The SESAR Randomized Clinical Trial. Matthieu Jabaudon 1 2, Jean-Pierre Quenot 3, Julio Badie 4, Jules Audard 1, Samir Jaber 5, Benjamin Rieu 1, Caroline Varillon 6, Antoine Monsel 7, François Thouy 8, Julien Lorber 9, Joël Cousson 10, Stéphanie Bulyez 11, Jérémy Bourenne 12, Ghada Sboui 13, Claire Lhommet 14, Virginie Lemiale 15, Belaïd Bouhemad 16, Clément Brault 17, Sigismond Lasocki 18, François Legay 19, Thomas Lebouvier 20, Arthur Durand 21, Julien Pottecher 22, Alexandre Conia 23, Delphine Brégeaud 24, Lionel Velly 25, Arnaud W Thille 26, Fabien Lambiotte 27, Erwan L'Her 28, Mehran Monchi 29, Antoine Roquilly 30, Aziz Berrouba 31, Franck Verdonk 32, Russell Chabanne 1, Thomas Godet 1 33, Marc Garnier 1 2, Raiko Blondonnet 1 2, Jérémy Vernhes 1, Vincent Sapin 2 34, Lucile Borao 1, Emmanuel Futier 1 2, Bruno Pereira 35, Jean-Michel Constantin 36; SESAR Trial Investigators. Collaborators, Affiliations Expand, PMID: 40098564

Mean arterial pressure after out-of-hospital cardiac arrest (METAPHORE): study protocol for a multicentre controlled trial with blinded primary outcome assessor.

Chudeau N, Saulnier P, Parot-Schinkel E, Lascarrou JB, Colin G, Barbar SD, Painvin B, Pichon N, Du Cheyron D, Marchalot A, Jarousseau F, Delbove A, Morichau-Beauchant T, Girardie P, Salmon Gandonniere C, Thille AW, Quenot JP, Bailly P, Goudelin M, Martino F, Nigeon O, Merdji H, Brechot N, Bourenne J, Bougouin W, Muller G, Jozwiak M, Doyen D, Rouanet E, Cariou A, Guitton C; AfterROSC Network; CRICS TRIGGERSep F-CRIN Network.BMJ Open. 2025 Apr 25;15(4):e096997. doi: 10.1136/bmjopen-2024-096997.PMID: 40280607 

Study protocol and statistical plan for the ICRAKI trial: Intermittent haemodialysis versus continuous renal replacement therapy for severe acute kidney injury in critically ill patients.

Gaudry S, Boubaya M, Louis G, Chaïbi K, Mégarbane B, Bohe J, Desgrouas M, Gele-Decaudin G, Joseph A, de Montmollin E, Camus C, De Prost N, Bailly P, Jaber S, Chudeau N, Lambour A, Robine A, La Combe B, Kimmoun A, Chevrel G, Argaud L, Nicolas J, Thiery G, Faguer S, Jozwiak M, Ricard JD, Contou D, Marzouk M, Chousterman B, Cadiet J, Bureau C, Zaleski ID, Rossignol P, Quenot JP, Queyrat CB, Dreyfuss D.Crit Care Resusc. 2025 May 6;27(2):100107. doi: 10.1016/j.ccrj.2025.100107. eCollection 2025 Jun.PMID: 40458742

A Restrictive Versus a Liberal Transfusion Strategy in Patients With Spontaneous Intracerebral Hemorrhage: A Secondary Analysis of TRAIN Randomized Clinical Trial.

Faso C, Gouvea Bogossian E, Bittencourt Rynkowski C, Moller K, Lormans P, Quintana Diaz M, Caricato A, Dabrowski W, Gonzalez Perez I, Steblaj S, Quintard H, Justo P, Righy C, Roman-Pognuz E, Huet O, Mahmoodpoor A, Blandino-Ortiz A, Junttila E, Funes N, Izzo G, Zattera L, Giacomucci A, Dibu J, Rodrigues A, Bouzat P, Vincent JL, Taccone FS; TRAIN Study Trial Group.Stroke. 2025 Sep;56(9):2617-2626. doi: 10.1161/STROKEAHA.125.050729. Epub 2025 Jun 17.PMID: 40525290 

Platelet Transfusion Practices in the ICU: A Prospective Multicenter Cohort Study.

van Wonderen SF, Raasveld SJ, Flint AWJ, Schenk J, van den Oord C, Reuland MC, de Bruin S, Bakker J, Cecconi M, Feldheiser A, Meier J, Müller MCA, Scheeren TWL, Hamid T, Piagnerelli M, Mahečić TT, Benes J, Russell L, Aguirre-Bermeo H, Triantafyllopoulou K, Chantziara V, Gurjar M, Myatra SN, Pota V, Elhadi M, Gawda R, Mourisco M, Lance M, Neskovic V, Podbregar M, Llau JV, Quintana-Diaz M, Cronhjort M, Pfortmueller CA, Yapici N, Nielsen ND, Shah A, de Grooth HJ, McQuilten Z, Vlaar APJ, Aubron C; InPUT Study Group.Crit Care Med. 2025 Sep 26;53(12):e2526-39. doi: 10.1097/CCM.0000000000006880. Online ahead of print.PMID: 41002230 

Multinational transfusion practices and outcomes in haematology patients admitted to the intensive care unit.

Schaap CM, Oomen LA, Raasveld SJ, Schenk J, de Bruin S, Reuland MC, van den Oord C, Bakker J, Cecconi M, Feldheiser A, Meier J, McQuilten Z, Scheeren TWL, Aubron C, Flint AWJ, Hamid T, Piagnerelli M, Mahečić TT, Benes J, Russell L, Aguirre-Bermeo H, Triantafyllopoulou K, Chantziara V, Gurjar M, Myatra SN, Pota V, Elhadi M, Gawda R, Mourisco M, Lance M, Neskovic V, Podbregar M, Llau JV, Quintana-Diaz M, Cronhjort M, Pfortmueller CA, Yapici N, Nielsen N, de Grooth HJ, Vlaar APJ, Biemond BJ, Shah A, Müller MCA; InPUT Study Group.Vox Sang. 2025 Nov 24. doi: 10.1111/vox.70153. Online ahead of print.PMID: 41285570

Perioperative red blood cell transfusion following high-risk oncologic surgery for tumor resection: a systematic review and meta-analysis.

Chapalain X, Zaïna M, Metges JP, Badic B, Sparrow RL, McQuilten Z, Huet O, Aubron C.Transfus Clin Biol. 2025 Oct 30:S1246-7820(25)00574-9. doi: 10.1016/j.tracli.2025.10.006. Online ahead of print.PMID: 41176214

Milrinone infusion for vasospasm treatment in subarachnoid haemorrhage: protocol for a double-blind randomised clinical trial - the MiVAR study.

Lasocki S, Lakhal K, de Courson H, Geslain M, Launey Y, Pottecher J, Trouiller P, Laffon M, Gakuba C, Parot-Schinkel E, Hamel JF, Campfort M, Gaillard T; MiVAR study group; ATLANREA group; SFAR research network.BMJ Open. 2025 Oct 28;15(10):e101483. doi: 10.1136/bmjopen-2025-101483.PMID: 41151960

Intubation of obese patients in the operating room with or without bag-mask ventilation: study protocol for a randomized multicenter trial (VENT OR NOT).

Znaïdi S, Deransy R, Asehnoune K, Le Penndu M, Rozec B, Jumel G, Lasocki S, Cadic-Pelletier A, Guinot PG, Duchalais A, Cirenei C, Abrard S, Beloeil H, Fortuit C, Landrin J, Porta Bonete G, Defrancq F, Péré M, Vourc'h M.Trials. 2025 Nov 11;26(1):492. doi: 10.1186/s13063-025-09114-z.PMID: 41219812 

Clinical Phenotypes of Critically Ill Patients with COVID-19 Infected with Omicron: A Nationwide Prospective Cohort Study.

Audureau E, Bay P, Préau S, Favory R, Guigon A, Heming N, Gault E, Pham T, Chaghouri A, Turpin M, Morand-Joubert L, Jochmans S, Pitsch A, Meireles S, Contou D, Henry A, Roux D, Le Hingrat Q, Kimmoun A, Hartard C, Pène F, L'Honneur AS, Guillon A, Handala L, Tamion F, Moisan A, Daix T, Hantz S, Delamaire F, Thibault V, Darreau C, Thomin J, Pawlotsky JM, Fourati S, de Prost N; SEVARVIR investigators.Infect Dis Ther. 2026 Feb;15(2):605-628. doi: 10.1007/s40121-025-01291-3. Epub 2026 Jan 6.PMID: 41493514 Free PMC ar

Best hypnotic drug choice for rapid sequence induction in the operating room: study protocol for a 3-arm superiority open-labeled randomized controlled trial with blinded evaluation of the primary outcome (the HyPnotiKs study).

Grillot N, Volteau C, Quillet P, Ambrosi X, Caillard A, David JS, Blet A, Bouzat P, Blanchet L, Bruneau N, Chebbi N, Saint-Genis Q, Figueiredo S, Guinot PG, Joosten A, Le Guen M, Labaste F, Lasocki S, Oudot M, Pommier M, Rousseleau D, Verdonk F, Tching-Sin M, Faurel-Paul E, Counille F, Cossé C, Flattres Duchaussoy D, Cinotti R, Roquilly A.Trials. 2026 Jan 16. doi: 10.1186/s13063-026-09452-6. Online ahead of print.PMID: 41546091 Free article.

Multinational transfusion practices and outcomes in haematology patients admitted to the intensive care unit.

Schaap CM, Oomen LA, Raasveld SJ, Schenk J, de Bruin S, Reuland MC, van den Oord C, Bakker J, Cecconi M, Feldheiser A, Meier J, McQuilten Z, Scheeren TWL, Aubron C, Flint AWJ, Hamid T, Piagnerelli M, Mahečić TT, Benes J, Russell L, Aguirre-Bermeo H, Triantafyllopoulou K, Chantziara V, Gurjar M, Myatra SN, Pota V, Elhadi M, Gawda R, Mourisco M, Lance M, Neskovic V, Podbregar M, Llau JV, Quintana-Diaz M, Cronhjort M, Pfortmueller CA, Yapici N, Nielsen N, de Grooth HJ, Vlaar APJ, Biemond BJ, Shah A, Müller MCA; InPUT Study Group.Vox Sang. 2026 Feb;121(2):169-179. doi: 10.1111/vox.70153. Epub 2025 Nov 24.PMID: 41285570 

High-Flow or Standard Oxygen in Acute Hypoxemic Respiratory Failure.

Frat JP, Quenot JP, Guitton C, Coudroy R, Gacouin A, Badie J, Demoule A, Contou D, Carteaux G, Ehrmann S, Jarousseau F, Sedillot N, Rigaud JP, Reignier J, Beloncle F, Dureau AF, Ferré A, Daubin C, Bourreau A, Delbove A, Pradel G, Fatah A, Colin G, Deniel G, Lamouret O, La Combe B, Prat G, Galerneau LM, Bourdin G, Julien G, Curtiaud A, Saint-Léger M, Turbil E, Reynaud F, Chamblet L, Ragot S, Thille AW; SOHO Trial Group and the REVA Network.N Engl J Med. 2026 Jun 4;394(21):2095-2106. doi: 10.1056/NEJMoa2516087. Epub 2026 Mar 17.PMID: 41841715 Clinical Trial.